Members of the iCFree consortium

The MICALIS institute (INRAE, AgroParisTech, Univ. of Paris Saclay) has several years of experience and published records in optimizing prokaryotic cell-free systems with machine learning for biomanufacturing and developing biosensors.

The I2BC institute (CEA, CNRS, Univ. of Paris Saclay) brings the know-how in the recombinant production of peptides and proteins and in the biological incorporation of ncAAs into peptides.

The CarMeN institute (Inserm, Univ. Claude Bernard Lyon 1) has a strong background in in vitro eukaryotic transcription and translation mechanisms.

Synthelis is a biotech that offers more than 10 years of expertise in protein production using cell-free systems. To date, the team has successfully produced over 230 difficult-to-express proteins using its cell-free technology.